What's causing the pain isn't this "triggering" injury any more – it's the complex communication system between nerves and the brain, which means that even after an injury has healed, the pain persists.
In contrast to toxin injection, which triggers whole muscle damage, the micropins induced several local myofiber injuries that, when repeated daily, trigger chronic injury.
Temporary hypoxia after injury triggers wound healing, but prolonged or chronic hypoxia delays wound healing.
Indeed, in our model, CPB was used to trigger kidney injury while direct renal ischemia-reperfusion was used in the other studies to initiate kidney injury [ 17, 29].
Damaging molecules can reach the proximal renal tubular cells in high concentrations and may trigger kidney injury followed by inflammation and oxidative stress and, finally, cell damage [9].
ROS generated from podocytes may trigger podocyte injury.
Experimental data have shown that mechanical ventilation can amplify or possibly trigger lung injury [ 1, 2].
Persistent NaV1.6 activity can trigger axonal injury within white matter axons during experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis (Craner et al., 2004).
However, neutrophil migration into the lungs is not sufficient to cause ALI, but rather activation of neutrophils is necessary to trigger the injury [ 17].
Smoking is a risk factor for coronary artery disease and triggers vascular injury by platelet aggregation and induces atherosclerosis through induction of oxidative stress.
The liver has an extraordinary regenerative capacity rapidly triggered upon injury or resection.
