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This meets what we consider to be the first requirement for a visual trigger hypothesis.
Together, these data are consistent with the trigger hypothesis whereby NAADP provides the trigger Ca2+ from acidic stores that is subsequently amplified by IP3Rs on the ER [ 13, 19].
These motions occur both at the beginning and end of turnover, and accompany the homolysis and recombination processes illustrated in Scheme 1.[ 9] To investigate the "substrate trigger" hypothesis set out above for Co C bond homolysis in EAL, we made three separate single-point mutations (see the Experimental Section and Figure S2).
The long-standing "trigger hypothesis" or two-pool model [ 13, 21] describes NAADP as a provider of an initial "trigger" bolus of Ca2+ that is subsequently amplified by Ca2+ release from the ER by virtue of the Ca2+ sensitivity of the IP3 receptor (IP3R) or ryanodine receptor (RyR), so-called Ca2+-induced Ca2+-induced (Ca2+).
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IRIDESCENT then scores the objects for relevance, significance, and interest, allowing the researcher to inspect the resulting connections to trigger hypotheses on new uses for existing drugs.
Toda et al. (2011) examined the Coulomb stress triggering hypothesis using 177 NIED F-net aftershock focal mechanisms.
These results support the triggering hypothesis that the static stress changes imparted by megathrust earthquakes cause seismicity changes.
Thus, we evaluate the triggering hypothesis by comparing the calculated Coulomb stress changes after the megathrusts to those during pre-seismic periods as background.
Changes in the focal mechanism distribution that can be correlated with static Coulomb stress changes due to megathrust earthquakes support the static stress triggering hypothesis.
The results supported the triggering hypothesis for the 2004 and 2011 giant earthquakes, while it was not clear for the 2010 earthquake.
The subcortical storage and triggering hypothesis suggests movements that can be prepared in advance of a "go" signal are stored and triggered from subcortical areas by a startling acoustic stimulus (SAS) without cortical involvement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com