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One common feature for all these conditions is the patient's reports of stress as a trigger for the development of pain [8, 9].
However, our case series and Mack's observation suggest that injury may be a trigger for the development of NDPH, and mechanisms responsible for it may be entirely different from that of post-traumatic headache.
Our study also confirms that increased inactivation of voltage-gated Na+ channels shown in an animal model of CIP [3] causes reduced membrane excitability, which is a trigger for the development of muscle weakness [2].
The trigger for the development of a new analysis tool was our need for 'on-the-fly' structure finding in the astrophysical simulation code (Teyssier 2002), in order to locate gas and/or dark matter clumps while the simulation is running.
Hypoxia is a trigger for the development of angiogenesis.
If so, such process could be considered as at least potential trigger for the development of cancer.
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Surgery and stress are two important triggers for the development of NDPH.
Environmental factors such as diet are critical triggers for the development of type 1 diabetes [ 5].
All of these features of sepsis are possible triggers for the development of AF [ 12].
However, despite our extensive knowledge of mature tumours, the exact triggers for the development of CIS cells remain unknown.
Further research to elucidate the triggers for the development of disease in this high risk young population in particular is clearly warranted.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com