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One trigger dose releases on average 1.2 2 ml of the product.
On average, one trigger dose releases 1.6 ml fTo wet a surface of 1 m2, five trigger doses are required.
In respect to drug prescription, elevated serum creatinine concentrations regularly trigger dose reduction for renally excreted drugs, although the converse-increasing drug dosing in response to low serum values-is infrequently considered in clinical practice.
cA rapid hemoglobin increase sufficient to trigger dose reduction was defined as ≥1 g/dL hemoglobin rise in a 14-day window in the absence of a transfusion during the previous 14 days.
Only when the opioid infusion rate had reached the 'propofol trigger dose' (8 ml/h; remifentanil: 12 μg/kg per hour; fentanyl 2 μg/kg per hour; Fig. 1) was propofol to be administered as an initial bolus dose of up to 0.5 mg/kg and an infusion of 0.5 mg/kg per hour, and titrated in 25% increments (0.25 mg/kg bolus dose + 0.125 mg/kg per hour rate increase; Fig. 1) to treat agitation.
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In the DPD2540 test, phenolics, membrane damaging toxic chemicals, for testing immobilized stress specific bacterial strains trigger dose-dependant bioluminescence increase within specific concentration.
In xOX2R-expressing cells, orexins (xOA and xOB) and xSCT could trigger dose-dependent [Ca2+]i elevations, but not intracellular cAMP accumulation, with EC50 values at 2.0 nM, 215 nM, and 146 nM, respectively (Fig. 6 and S10).
This article oriGivenly appeared on VICE US.
An assessment of renal function is common, with evidence of acute or chronic renal impairment often triggering dose reduction to avoid drug accumulation.
In vivo, the multi-layered bioactive collagen-fibrin scaffolds loaded with the IGF-1 variant triggered dose-dependent functional host smooth muscle cell invasion and bundle formation with re-urothelialization 4 weeks after surgery in a rat model.
Secretion was triggered dose-dependently by forskolin, with EC50s of 1.9 ± 1.7 µM and 1.5 ± 0.4 µM respectively.
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