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The different associations of TFs with their cis-regulatory elements on the DNA can trigger, counteract or modulate these regulatory states of genes.
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We previously demonstrated that TLR9 triggering counteracts lytic EBV reactivation in BL cells and promotes latent EBV that is associated with B-cell lymphoproliferation.
These data strongly suggested that protein-induced hypophagia was not mediated by an enhanced activity of the MCS, but rather support the hypothesis according to which a decreased MCS tonus is actively triggered to counteract the hypophagia effect, in order to maintaining the former food intake.
Sensors in the lens trigger motors that counteract shake.
Here, an external signal works as a trigger mechanism that counteracts internal damping, causing the auto-excitation to spread its activity in the system While these differences in the "mechanics" of the signaling networks are considerable, the overall dynamics is surprisingly similar.
However, rapid elevations in blood pressure trigger baroreflex mechanisms counteracting the heart rate increase.
At low concentrations, netrin-1 preferentially binds to CD146, whereas at high concentrations, netrin-1 could bind to UNC5B and triggers signals that counteract CD146 downstream signals to inhibit the growth of blood vessels.
On the other hand, ALF also triggers survival pathways to counteract death signaling.
In murine mature macrophages, Twist1 2 are also implicated in an anti-inflammatory feedback loop triggered by IFNα to counteract production of TNFα.
Tumour cells must therefore have acquired molecular mechanisms to counteract apoptotic triggers in order to survive under unfavourable conditions and to be able to form solid tumours.
The primary response observed was the overwhelming induction of TLR2 to counteract B. pseudomallei, which we propose, subsequently triggered the activation of many inflammation-biased genes important in attracting neutrophils and monocytes to the site of acute inflammation.
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