The term "trigger agent" is correct and can be used in written English.
It refers to a person or thing that initiates or activates a process or event. Example: The media was the trigger agent for widespread protests against the government's policies.
Another option is that CPA itself modulates directly the effect of the trigger agent.
This new trigger agent may, therefore, offer a completely new, "natural" pharmacological option for ovulation induction in ART.
Interestingly, some cases of EFS after hCG triggering are solved by changing the trigger agent to GnRH agonist in GnRH antagonist cycles [ 45].
The term 'anaphylaxis' has been used for all types of acute life-threatening illness triggered by abnormal sensitivity (hypersensitivity) to a trigger agent, and for apparently spontaneous attacks with similar features (idiopathic anaphylaxis).
The histopathological examinations revealed a myopathic tissue syndrome in combination with cell clumps indicating a possibly neurogenic component in 1 MHEh patient, who had received succinylcholine as sole trigger agent.
Currently, various short-acting GnRHa preparations are used as trigger agents.
At this point the question is 1) can be assure the MHN patients regarding GA with trigger agents?
However, it is completely unclear why many MHS individuals may suffer from MH only after several uneventful exposures to trigger agents during anaesthesia.
In susceptible individuals, exposure to trigger agents such as volatile anesthetics and depolarizing muscle relaxants, typically administered to induce or maintain general anesthesia, may lead to a hypermetabolic muscular syndrome [ 1].
These findings have stimulated a long debate on the possibility that HCV could be considered at least one of the candidate viruses to work as trigger agents for pSS.
Further investigations with focus on extrinsic and intrinsic factors that modulate SERCA activity may be helpful to understand why MH patients may have had several anaesthesias including trigger agents without a significant reaction while developing a fulminate MH crisis at another occasion.
