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Blinded, randomised-controlled trials were retrieved from Scopus and Cochrane Central Register of Controlled Trials databases.
A total of 1177 trials were retrieved and 75 met the criteria for inclusion in the review.
From these systematic reviews, data for 1 012 trials were retrieved; 143 duplicate reports and reports of 129 nonrandomised trials were excluded.
Six trials were retrieved including 875 patients.
In addition, registered but not yet published trials were retrieved.
From ClinicalTrials.gov, 149 273 records of clinical trials were retrieved.
Similar(47)
In total, liver biopsies from 228 infected patients in the DITTO-HCV trial were retrieved and evaluated.
If multiple publications of the same trial were retrieved, or if there were data inconsistencies between publications of the same trial, all publications were included, but only the most recent and the most informative data were used.
Annual hazard rates in the BIG 1-98 trial was retrieved as previously described [25].
Titles and abstracts of all identified studies were screened, and the full text of each potentially relevant trial was retrieved.
The included trials were combined with the HSSS12, the HSSS123, and NBSS to determine the number of trials that were retrieved by each.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com