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Five systematic reviews were identified from which 41 analyzable trials were extracted.
Finally, a total of 29 references reporting trials were extracted.
Approximately 300 trials were extracted for each participant.
Details of the trials were extracted using standardised tables.
In addition, general characteristics of the studies and outcomes of the trials were extracted.
Mean effect data from crossover trials were extracted at the end of the initial phase.
Similar(45)
In addition, case-fatality ratio of PEP in these trials was extracted with report of case-fatality ratio in two trials [ 4, 7].
NA = not applicable In addition, case-fatality ratio of PEP in these trials was extracted with report of case-fatality ratio in three trials [ 20- 22].
The validation set containing 670 drugs and their targets annotation was created as follows: (a) compounds labelled as approved drug or drug in clinical trial were extracted from ChEMBL database, (b) for each drug, target list was constructed by comparing SMILES string of drug to SMILES of bioactive compounds of targets used in the PPB.
For continuous outcomes (e.g. left ventricular ejection fraction), the mean change and standard deviation for the mean in each group of the trial were extracted along with the total number.
Hospital invoices from all patients included in the trial were extracted.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com