Furthermore, the RCT networks are "small worlds": trials are connected through a small number of ties, yet there is much clustering among subsets of trials.
The importance of the small world finding is that all trials are connected through a small number of ties enhancing the argument that treatment discovery is a social enterprise.
Within hours of the discovery, investigators interviewed one of the admitted drug dealers whom Mr. Luna was prosecuting in Baltimore, and officials said they were investigating the possibility that the trial was connected to his death.
Once removed the endotracheal tube from patients, who were extubated in our ICU after successful weaning trial, was connected to a filter (Hygrobac), and both were attached to ASL 5000 active servo lung (IngMar medical).
The Continuing Adventures of Quinn Perkins Lowes: "The 'Who is Quinn?' and the Quinn Perkins trial is connected to such a huge conspiracy that's so much bigger than who she is, and how large does it go?
We conclude that the treatment discovery process in RCTs could be explained by a small world network model according to which each trial is connected to any other trial in the network through a small number of steps.
Thus, the process of discovery of new therapeutics in cancer under the NCI umbrella, represented either as a shared characteristic network or a preferential attachment network, fits a pattern of connection that can be described as a small world network in which each trial is connected to any other trial in the network through just a few ties.
Moreover we have not further investigated whether or how the patients' readiness to take part and complete the trial was connected with a perception of high quality of the GSD intervention as expressed by one patient in a case study.
Similarly, we found several instances where author teams focused on both preventive non-vaccine and preventive vaccine trial research were connected to therapeutic and translational research (supported by ACTG) research groups.
A weighted clinical trial-based cancer network was also constructed (herein denoted as clinical trial cancer network), where two cancers were connected if there is at least one FDA approved drug (approved for at least a cancer) in the clinical trial data for both cancers (Dataset S3, Table S3).
