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In order to perform a systematic review, categorisation of similar trials was required.
ClinicalTrials.gov has provided comprehensive information since 2007, when registration of clinical trials was required by the FDA.
Doctors at both university hospitals thought enhancing public awareness of clinical trials was required for overcoming the obstacle.
Clinics in Orthopaedic Surgery, the American Journal of Bone and Joint Surgery, and BioMed Central explicitly stated that registration of all clinical trials was required.
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I therefore support the conclusions that further data based on more realistic field trials is required".
The trials are required before the Food and Drug Administration reviews the drug for possible approval.
Under a special humanitarian rule for rare diseases, only limited clinical trials were required.
Hence, large trials are required.
Large-scale trials are required to produce Level 1a evidence.
Larger clinical trials are required to validate these findings.
Further evaluation in the form of randomised trials are required.
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