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The categories number of trials administered, total number of correct answers, total number of errors, number of perseverative responses, number of perseverative errors, number of categories completed, number of trials to complete the first category, and failure to maintain set were considered for analyzing gains related to cognitive flexibility in the present study.
Scores were based on number of trials administered, total number of correct responses, number of errors, number of perseverative responses, number of perseverative errors, number of non-perseverative errors, number of categories completed, number of trials to complete the first category, conceptual level responses, failure to maintain set, and learning to learn.
The SUPPORT trial was the first of the oxygen trials to complete recruitment.
Traditional drug development programs in industry have focused on the largest markets, such as skin infections and CAP, since they are perceived to bring the largest return on investment and to be the easiest trials to complete.
Thus, if our subjects were merely referring to the visual aspect of the stimuli and making a mere visual discrimination, they would have required more trials to complete the tasks.
Across the remaining 139 participants, the mean number of trials to complete the task was 106.2 (SD 21.0), the mean of categories completed was 5.0 (SD 1.5); this performance was not significantly different between groups (ts <1.4, ps > .1).1
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A high recruitment rate will be required for the trial to complete on schedule.
The RCT comprises an exploratory trial, to complete the modelling and piloting phase of the MRC 4-phased framework [ 26].
Unfortunately, with the preference for less-invasive therapies and procedural selection based on operative risk, it might be a difficult trial to complete with regard to patient recruitment and enrollment.
The Ethics Committee did not approve the proposed use of a twofold written consent incorporating a request for those who declined to participate in the trial to complete a baseline questionnaire at the hospital.
The number of trials necessary to complete the discrimination task (4800 trials) is very large.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com