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Large-scale trials to change these risk factors in populations at high risk, as has been done for heart disease, should now be implemented, she added.
Policy makers needed more than evidence from trials to change from the time-honoured IRS strategy that they perceived was working.
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So far — and with the caveat that details could emerge at trial to change this — there has been little public outrage.
Summary of results (Fig. 3) Given that the peak hazard for local recurrence is early in all postmenopausal women, we would not expect the result of the TARGIT-A trial to change.
Since the original Pygmalion study, there have been very few interventions in the teacher expectation field and none that have been randomized control trials designed to change teacher practices to reflect those of high expectation teachers.
The estimation of an effect size is an important step in designing an adequately powered, feasible clinical trial intended to change clinical practice.
The second major protocol category is an interventional study or clinical trial designed to change the course of a disease through a therapy or the use of instrumentation.
The largest of these studies, the SUPPORT trial failed to change physicians' behaviors or measurable outcomes [ 4].
But a new generation of brain-imaging studies and robust clinical trials is helping to change that.
Well designed, prospective trials are warranted to change the target approach from a general to an individual treatment strategy.
If all civil cases are not alike, then maybe those courts looking to streamline civil jury trials should look to change those types of cases that do not provide a civic boost.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com