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There is a need for well designed, good quality randomized trials to answer other questions related to this intervention and increase the precision of future systematic reviews.
This under-reported phenomenon has fundamental impact on the design of RCTs and can have an adverse impact on the statistical power of these trials to answer important questions about therapeutic strategies.
In 2003 the International Breast Cancer Study Group (IBCSG) initiated the TEXT and SOFT randomized phase III trials to answer two questions concerning adjuvant treatment for premenopausal women with endocrine-responsive early breast cancer: 1-What is the role of aromatase inhibitors (AI) for women treated with ovarian function suppression (OFS)?
But not all observers see the data as positively, and some large questions remain for further data analysis and future trials to answer.
There is increased interest nationally in multicenter clinical trials to answer questions about clinical effectiveness, comparative effectiveness, and safety in real-world community settings.
Clinical trials to answer these questions are urgently required.
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We would have liked to see Colonel Gaddafi going on trial to answer for his misdeeds".
We would have liked to see Gaddafi going on trial to answer for his misdeeds".
He will stand trial to answer to the original claims in an effort, he says, to finally clear his name.
Nonetheless, these data indicate that long-term dietary change was achieved in this clinical trial setting and reinforce the potential of the ongoing trial to answer questions of public health importance.
The findings needed to be confirmed in a trial to answer the question about anemia drug risk, Dr. Ayalew Tefferi, a Mayo Clinic hematologist and the study's lead investigator, said in a statement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com