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Higher values thus reflected a tendency during later trials to adjust heading in the direction of an upcoming turn, collapsed across left and right turn directions.
We applied efficacies of statins and other cardiovascular drugs from meta-analyses of randomized trials to adjust the effect of fenofibrate in a penalized Cox model.
In subsequent analyses, a method that uses historic effect size estimates of placebo-controlled trials to adjust the HR observed when working with a nonplacebo control was implemented.
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For example, Bayesian adaptive trials designed to adjust in a prespecified manner to changes in clinical practice could motivate people and their health care providers to view clinical trials as more applicable to real-world clinical decisions.
Our solution is to numerically test the models by a trial and to adjust the values of the meso-level parameters of particles until the test results are in accord with those of real samples.
Scientific jury research is employed for three general purposes: to evaluate an existing jury venue or venire, to aid in selection of the trial jury, and to adjust trial strategy to fit the seated jury.
In addition, Adjuvant! calculates the absolute survival benefit of any proposed adjuvant therapy by using treatment effect estimates from meta-analyses and randomized controlled trials to proportionately adjust its mortality and recurrence rates.
Sample sizes for cluster-randomized trials were inflated to adjust for clustering.
Where trials used methods to adjust for attrition bias, these data were used in preference to data from completers.
Our findings strengthen the importance of a control arm in biomarker trials in order to adjust for the biological and technical variability of biomarkers.
2 3 We found little association across disease areas between burden of disease and quantity of randomised trials, with extreme levels of variation in the ratio of trials to disability adjusted life years among diseases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com