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In three of five trials the hypothesis tests found evidence against the MCAR assumption.
When such figures are compared to a 20% intention-to-screen-based mortality reduction reported by FOBT screening trials, the hypothesis of FOBT screening being effective only through colonoscopies recommended for spurious FOBT positivity is hardly acceptable.
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Current clinical trials test the hypothesis that its use at the time of islet transplantation might be of help in preserving islet mass (41).
Prospective, randomized trials to test the hypothesis are warranted.
"There is even a cardiovascular trial, the hypothesis of which is that testosterone actually makes cardiac risk factors better," said Dr. Snyder, who characterized the TOM results as an aberration.
In a field trial the hypothesis was tested that aboveground DMY and MHY are affected by the frequency of cutting and cutting height, and that these management effects interact with the tall wheatgrass germplasm.
Had the initial study been a randomised controlled trial, the hypothesis formation could have occurred in a single study.
In this retrospective analysis of KRAS mutation types from a previously reported phase II trial, the hypothesis that MG1 will have a better response to selumetinib+docetaxel than MG2 was evaluated.
The aim of this study was to test, by means of a randomized controlled trial, the hypothesis that the use of a birthing seat during the second stage of labor, for healthy nulliparous women, decreases the number of instrumentally assisted births and may thus counterbalance any increase in perineal trauma and blood loss.
Objectives: We conducted a 1-year randomized controlled trial to test the hypothesis that growth hormone (GH) improves the clinical status of children with cystic fibrosis.
We designed a double-blind randomised controlled trial to test the hypothesis that an intracavity injection of the anti-inflammatory corticosteroid triamcinolone would inhibit seroma re-accumulation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com