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Patients with rare diseases are often treated in multicentric trials spread over national boarders.
Evidence of mortality reductions began to appear, cancer-driving mutations became measurable, many novel drugs were registered, the methodology of clinical trials spread through health systems, targeted drugs and immunotherapy entered into the mainstream of therapeutics, and treatment goals started to shift from cure to chronic control.
Each subject performed 324 trials, spread across 4 blocks, in pseudo-random order.
Hence, in total, every female had eight extra-pair trials spread over four breeding attempts involving two different partners and four different extra-pair males.
In order to contribute to resolve the genetic basis of photoperiod sensitivity in maize, a set of 201 recombinant inbred lines (RIL), derived from a temperate and tropical inbred line cross were evaluated in 5 field trials spread in short- and long-day environments.
There were eight catch trials spread throughout the scanning session one at each target position and always at the end of a block.
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After a trial spread out over two weeks, the jury deliberated for a few hours on Wednesday afternoon and Thursday morning before returning its verdict.
Media attention on the trial spread beyond the provincial and national borders: Time magazine published at least two articles on the trial in the United States, and the Daily Mail and Paris Midi covered it from across the Atlantic.
The man he has to thank is not the hapless PR Raymone Bain, who spent the trial spreading the word of Jacko's innocence from the parking lot of the courthouse all the way up to the Larry King Show and was rewarded with the sack, but his silver-haired defence lawyer Tom Mesereau.
While many companies and researchers resort to Excel spreadsheets, email, and phone calls, goBalto seeks to streamline the process, which can take up to 18 months because many clinical trials are spread out through several countries.
Although many major pharmaceutical companies, government agencies, and foundations already require anonymized patient-level clinical trial data from studies they fund to be made publicly available, the practice is still far from universal, and the information from these trials is spread across different databases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com