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Low vitamin D intake and levels have been associated with increased joint symptoms in some observational studies but the findings are mixed and evidence from randomized trials sparse.
Several trials support the benefit of SCs in patients with chronic ischemic cardiomyopathy (ICMP), although the sample sizes have been small and the number of trials sparse.
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Metal ceramic restorations are widely used in prosthodontics, but long-term data on their clinical performance in private practice settings based on prospective trials are sparse.
Therapeutic approaches for MIDD are not consensual as clinical trials are sparse.
The overall higher risk of bias of the trials and sparse data warrant cautious interpretation of the results.
Moreover, few previous studies directly compared the effects of sulfonylureas and metformin on cardiovascular events, and the evidence from randomized clinical trials is sparse (12).
However, good quality research into effective recruitment to trials is sparse and there is a need for a more comprehensive evidence base.
Because well-designed, randomized, controlled clinical trials are sparse in AGC, an exploratory, or retrospective analysis seems to be an important source of data to allow the definition of optimal treatment, enhance patient counseling, and generate hypotheses for future studies.
Expert consensus is recognized as a viable method of providing a basis for decision-making in situations where evidence from other sources, such as randomized trials, is sparse or non-existent [ 10].
The overall high or unclear risk of bias of the trials and sparse data in this meta-analysis highlight the lack of firm evidence for the benefits of SUP in neurocritical care patients.
Because there were few dose-ranging trials and sparse outcomes for adverse events, and to avoid multiple comparisons with the same placebo group, we combined dosage groups within each trial to make one contrast with placebo according to the Cochrane Handbook for Systematic Reviews of Interventions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com