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Intervention optimization designs such as fractional factorial and sequential multiple assignment research trials (SMART) are particularly valuable when the intervention development questions involve combinations or sequences of intervention components [18].
Sequential Multiple Assignment Randomized Trials (SMART), use experimental design principles to answer questions for building adaptive interventions including whether, how, or when to alter treatment intensity, type, or delivery.
Sequential, multiple assignments, randomized trials (SMART) can be used to test the decision rules for an adaptive intervention [ 105].
Evidence of mortality reduction has come from a number of meta-analyses of trials (Smart et al, 1995; Hendrick et al, 1997; Kerlikowske, 1997; Moss et al, 2006).
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The sequential multiple assignment randomized trial (SMART) is particularly useful in developing adaptive treatment strategies.
The second is the Sequential Multiple Assignment Randomized Trial (SMART), which is an innovative research design especially suited for building time-varying adaptive interventions.
Because subjects in RAD are potentially randomized multiple times with randomizations occurring at crucial points of the disease process, RAD is an example of a Sequential Multiple Assignment Randomized Trial (SMART) (Lavori and Dawson 2004; Murphy 2003).
A sequential multiple assignment randomized trial (SMART) is a novel trial design that can test these dynamic treatment regimens and lead to treatment guidelines that more closely mimic practice.
EM: Electronic Monitoring HIV: Human Immunodeficiency Virus MDI: Metered-Dose Inhaler MEMS: Medication Event Monitoring System RCT: Randomized Controlled Trial SMART: Supporting Medication Adherence in Renal Transplantation The author(s) declare that they have no competing interests.
Consequently the Study of Mental Activity and Regime Training trial (SMART) was designed and implemented to examine the isolated and combined benefits of cognitive training and resistance training, and to provide novel, comprehensive data on possible proposed links between cognitive improvement and brain and whole-body-adaptation to resistance and cognitive training.
UKBA haven't published the results of their trials of smart gates at Manchester and Stansted airports.
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