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Provided sponsors capture both early and late outcomes in multinational trials, separate analyses for US and European authorities are possible, and the same study could satisfy both sets of requirements [18].
For instance, in the name of data purity, scientists had always kept experimental treatment trials separate so that they could clearly and accurately see each drug's effect on health.
On 30% of trials (separate from those with a visual target) an auditory target was presented that was identical except louder.
Our overall strategy was to keep the two trials separate and fit a sufficiently complex model in order to account for between-trial correlation to maximize the use of information and statistical power.
Single neuron firing rates from the 124 DLPFC units were explained using a model that contained separate 6 terms: separate constant terms for effort and delay trials, separate LFP-derived PC2 weights from OFC for delay and effort trials, and separate LFP-derived PC2 weights from ACC for delay and effort trials.
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Now a review of 16 randomized controlled trials separates the treatments backed by scientific evidence from those that are not.
Figure 3B depicts the mean accuracy on these trials, separated by condition.
The study consisted of two 15-day diet trials separated by a ≥1-week washout period.
Figure 3A provides the mean performance on these trials, separated by condition (see Appendix B for the data on all other trial types).
Participants visited the laboratory on four occasions, one anthropometric and familiarisation session and three experimental trials separated by > 2 < 7 days.
Sixteen healthy males participated in a single-blind, placebo-controlled cross-over design study involving 4 experimental trials (separated by ≥7 d).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com