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Guidelines for publishing clinical trials require that all adverse outcomes of a medical intervention should be published.
The Olympic trials require that track and field athletes finish among the top three to qualify for the Summer Games.
Clinical trials require access to patients, physicians, and health care organizations, areas where Solvay has less of an advantage.
Oral trials require prosecutors to do a better job of gathering evidence and building a case.
Cancer clinical trials require the voluntary participation of patients for their adequate development.
Since survival trials require large numbers of patients, it raises the question of why Genentech set that as the goal in such a small trial.
Randomized controlled trials require a lot of resources and are not designed to answer all research questions.
Thus, therapies that are safe and effective in murine models may be neither safe nor effective in human trials, and subjects for such trials require careful selection.
Screening and tracking subjects and data management in clinical trials require significant investments in manpower that can be reduced through the use of web-based systems.
Evaluating candidate biomarkers in the exploratory phases of drug development and investigating surrogate endpoints in confirmatory trials require the establishment of a statistical and inferential framework.
Non-inferiority pivotal trials require that, as far as practicable, the same techniques are used as were employed when the trials assessing the standard regimen were conducted.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com