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When rat responses to the first 10 presentations of the transformed prototypes were considered (early trials), recognition performance was positively and significantly correlated with the previously measured priming magnitude produced by the prototypes' views (see Fig. 8D, red diamonds).
Research challenges in the rare disease area include identification of uncommon patients for clinical trials, recognition of the clinical spectrum of a given disorder and understanding genetic and environmental factors that influence disease manifestations (phenotype).
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This dose resulted in an impairment of spatial memory in a two-trial recognition task 11 days later.
We studied here the action of this new compound on recognition memory in young and old rats, using a two-trial recognition task designed to test both place and object recognition.
In the present study, we assessed the effects of a selective 5-HT4 receptors agonist, RS 67333 [1 4-amino-5-chloro-2-methoxyphenyl -3- 1-n-butyl-4-piperidinyl -1-propanone], in a two-trial recognition task designed to test place or object recognition memory.
The following experiments examined whether sample repetition might reverse the one-trial recognition deficit.
In this workplace trial, recognition of the disorder in a vignette improved 10% in the intervention group compared to 1% in the wait-list control group.
The PRh rats were highly impaired on these specific trials, which taxed one-trial recognition (simple effects second trial: Experiment 2a, F1,80 = 53.12, P< 0.001; Experiment 2b, F1,100 = 45.52, P< 0.001).
To control for general cognitive functioning, we investigated the effects of the (putative) anxiolytic pre-treatment in a one trial object recognition test in both strains as well.
Soontornniyomkij and colleagues (2010) reported that, in mice, reduced hippocampal formation levels of FKBP51 and a reduction in the ratio of FKBP51 to FKBP52 are associated with impaired performance in a single-trial object recognition test.
The optimal hyperplane for classification obtained by the training data is independent of CSI and source messages, and thus, it can be applied to all of the trials of recognition.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com