Exact(19)
In a commentary published online Wednesday by The New England Journal of Medicine, agency officials wrote that the results of the new trial, as well as of previous trials, "raise major concerns" about the use of the drugs to treat the anemia caused by chronic kidney disease.
Hasty trials raise fears of possible miscarriages of justice.
Nonetheless, economic evaluations alongside international clinical trials raise specific questions of methodology with regard to both the design and the analysis of the results.
He argued that Goldacre had gone "over the top" in devoting a whole chapter (chapter five) to recommending large clinical trials using electronic patient data from general practitioners, without fully pointing out how problematic these can be; such trials raise issues, for example, about informed consent and regulatory oversight.
The recent results from the ACCORD and INVEST trials raise questions about the impact of intensive hypertension management.
These trials raise important and difficult questions.
Similar(41)
This plan is another candidate for elimination, or perhaps it should be limited to encompass only very widely prescribed drugs whose clinical trials raised a safety signal(s).
But the committee, set up by the National Institutes of Health to help oversee gene therapy clinical trials, raised questions about the process used to enroll the woman in the study.
Nevertheless, noticeable protection against the disease – which kills around 500,000 children under five every year – was achieved in recent trials, raising hopes that one of the planet's greatest health scourges could soon be tackled.
Rushing them into widespread use without large-scale trials raises hopes and concerns.
In pediatric oncology, the conduct of those trials raises specific challenges, as the disease is rare with limited therapeutic options.
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