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Even though recent trials question the long-term benefit of an interventional approach in general, they on the one hand do show benefit for the subgroups we focused on (M1, carotid T) [36].
We inquired through a 4 tier scale about the merits of participating in clinical trials (Question #8) and about the difficulties faced in conducting such trials (Question #10) using 10 and 11 subordinate items respectively.
Although raltitrexed may have a place in the treatment of some patients who cannot tolerate 5-FU (Taylor, 2000), the results of clinical trials question its efficacy compared to commonly used 5-FU/LV regimens.
They should be able to activate their prior knowledge in terms of linking the topic to their past and present experiences of having been involved in research protocols and recruitment of subjects in research studies and clinical trials (question of how is it relevant).
Similar(54)
Despite demonstrated efficacy in clinical trials, questions remain about the safety and clinical effectiveness of various treatment options given patient characteristics, conditions, preferences, and their desired outcomes.
However, subsequent randomized controlled trials questioned this hypothesis.
Careful selection of participants ensures that answers to the trial question will be applied appropriately outside a clinical trial and also helps to exclude participants for whom the approach may be unduly dangerous.
For recurrent anaplastic astrocytomas, the optimal chemotherapy regimens remain an active clinical trial question.
Factorial trials maximise the efficiency of a trial by including more than one trial question into a single trial population.
For newly diagnosed anaplastic astrocytoma, the optimal application of radiation and chemotherapy is an active clinical trial question.
GPs indicated they forgot to approach patients with acute LBP to participate in the trial (question 5), but when they did approach patients to participate, patients showed neither an interest nor disinterest in participating (question 6).
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CEO of Professional Science Editing for Scientists @ prosciediting.com