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Generic versions of traditional brand-name drugs can be approved without human clinical trials, provided the copies are chemically and biologically equivalent to the original products.
The Nuremberg trials provided the basis for the modern law of war crimes and crimes against humanity, and a model for recent international prosecutions for such crimes.
The success of these trials provided the foundation for clinical trials, including recent clinical successes using TCR-engineered T cells to target New York esophageal squamous cell carcinoma (NY-ESO-1).
For iron deficiency, the results of intervention trials provided the effect estimate.
All of the included studies compared tofacitinib with placebo, and additionally, two trials provided the comparison with adalimumab.
At the end of the clinical trials, provided the results are satisfactory, an application for marketing authorization can be submitted to the NRA.
Similar(49)
The trials provide the drama, the errors the comedy, and their overlap the pathos.
Randomized clinical trials provide the most internally valid evidence for medical decision-making.
The progression of Eltrombopag into clinical trials provides the final validation of our approach, wherein a dose-dependant stimulation of platelet production is observed in humans.
Randomized controlled clinical trials provide the optimal method to evaluate new therapies, by comparing a therapy with a placebo or another therapy without selecting patients for specific therapies.
Randomized controlled clinical trials provide the most solid basis for the establishment of broad therapeutic principles.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com