Exact(1)
Significant delays in the provisional time frame guidelines were caused by 1° Regulatory aspects; 2° Insurance modalities; 3° Negotiation of sponsorship delegation contracts; 4° Site specific logistics for biobanking; 5° Clinical trials operational management.
Similar(59)
Despite this evolution, the design and data quality derived from imaging within clinical trials are not ideal and gaps exist with paucity of optimised methods, constraints of trial operational support, and scarce resources.
During the course of the fluoridation trial, operational management responsibility for the fluoridation plants at PWC changed three times.
To date, field trials and operational beds have primarily used wood media as the carbon source; however, the use of alternative more labile carbon media could provide for increased removal rate, lower installation costs and reduced bed size.
Randomised trials utilising operational frailty definitions with clinically relevant endpoints are required to inform therapy in this population.
With evidence to date primarily case study based, the extent to which various influences on recruitment to trials are operational in National Health Service (NHS) mental health settings is unknown.
Most recently, the Rwandan government adopted a national Health Sector Research Policy to guide work from clinical trials to operational and social science research [ 17].
It has also explicitly set out to learn and document it's learning with partners from abroad: " Most recently, the Rwandan government adopted a national Health Sector Research Policy to guide work from clinical trials to operational and social science research.
Drug trials and operational studies under the Clinical Research Initiative provided not only empirical evidence on clinical outcomes of tested ART protocols, but also the information on treatment and care delivery for PLWHA in peripheral settings, which was helpful to the development of HIV services in later phases [ 22].
Given the poor coverage of current ITN programmes as a means to prevent infection among school aged children, pragmatic trials or operational investigations of the impact of ITNs delivered to children attending school should be compared to the provision, separately or in combination, with drugs used for intermittent presumptive treatment.
The data extraction, interim analysis and the following phase III CV meta-analysis were performed by a group independent from the EMPA-REG OUTCOME™ trial team, so that the trial's operational team and the academic Steering Committee remained blinded to the results.
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