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It is important for investigators, regulatory agencies, ethics bodies and funding agencies to keep these issues in mind as they move forward in designing the clinical trials of the future.
If the modulation of surrogate response biomarkers such as IEN can be validated as being correlated with a reduced cancer incidence in phase III trials, then prevention trials of the future might use IEN instead of cancer incidence as their main study endpoint.
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The measure is expected to address six areas of reform: integrating patients' perspectives into the regulatory process, modernizing clinical trials, fostering the future of science, investing in advancing research, incentivizing the development of new drugs and devices for unmet medical needs and supporting digital medicine.
Perhaps a withdrawal phase should be part of clinical trials in the future.
AIDAI is the first validated instrument designed to standardise assessment of AIDs activity across trials, and to facilitate comparison and meta-analysis of clinical trials in the future.
He believes the main role of pet clinical trials in the future will be to help pharmaceutical companies like his minimize the risk of drug development.
Microbiome profiling, therefore, may well become an inevitable arm of all clinical trials in the future.
This review highlights the potential importance of considering S. aureus bacteremia separately from other pathogens in the context of adequately powered trials in the future.
But they lead me to wonder about the design of preventive-vaccine clinical trials in the future.
Large-scale, multicenter clinical trials are the way of the future for young investigators wishing to address complex questions related to brain development and to discover safe and effective interventions for kids living with neurodevelopmental disability.
Based on experience gained in both research and industrial trials, the future of data center networking must include careful consideration of the interactions between the important aspects mentioned above.
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