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The few trials of prevention therapies — involving ginkgo biloba, women's hormone replacement treatment and anti-inflammatory drugs — have involved people not guaranteed to get the disease.
Magnetic resonance colonography with Fluorinert enema and intravenous contrast enhancement will be useful in the study of the initial stages of colon cancer and will reduce the number of animals needed for preclinical trials of prevention or intervention.
This will be particularly important to allow adequately powered phase III trials of prevention or intervention.
Clearly, trials of prevention and therapy are not comparable because widely disparate definitions have been used.
However, clinical trials of prevention strategies may have greater power if conducted among patients at highest risk.
Multiple novel therapies have emerged as promising candidates for trials of prevention or early treatment of ALI.
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However, a systematic review evaluating studies on treatment of PONV stated that there is a discrepancy between the plethora of trials on prevention of PONV and the paucity of trials on the treatment of established symptoms [ 10].
There is a discrepancy between the plethora of trials on prevention of PONV and the paucity of trials on treatment of established symptoms.
Clinical relapse and severe endoscopic recurrence are the main outcomes in the evaluation of trials on prevention of recurrence.
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This paper has identified patient and practice predictors of referral to a lifestyle modification program among high risk patients participating in the intervention arm of a trial of prevention of CVD in primary care.
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