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Although the methodological quality of trials was variable, the results were in general consistent between the trials of better and poorer quality.
Recent systematic reviews and meta-analyses identified the need for further controlled trials of better quality and larger sample size studies, including evaluation of type, duration, frequency and intensity of physical therapy.
Sensitivity analysis (not shown) —When we restricted the analysis to trials of better methodological quality (that is, adequate methods of randomisation and allocation concealment) there was no change in results for clinical failure (n=105) 71722 or microbiological failure (n=45).
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The later trials are of better quality than earlier trials.
Although more clinical trials of a better design and with larger samples are necessary to allow definitive conclusions to be drawn, PRF is a potentially useful biomaterial.
Several studies 24 25 that compared the content of published reports with their protocol found that the methodological techniques in the actual trial were of better quality than reported in the final publication.
A series of large-scale field trials to better understand the explosion characteristics of silane air was conducted by the G-13 Silane Task Group under the direction of the Compressed Gas Association (CGA) and its guidelines.
As such, the number of censored patients at each time interval should be routinely reported in randomised trials to better understand the implications of censoring.
We analyzed the 13-yr screening and outcomes data from the 151 participants who died of PCa in the screening arm of the trial to better understand how randomization to screening failed to prevent PCa death in these men.
Among those 22 trials, the additional benefit of "better safety profile" was most often claimed (12 trials; 55%).
Some parents will see trials as a threat to their child or fear regretting their decision, whilst others see trials as offering hope of better treatments for their child.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com