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In clinical trials no significant differences in systematic symptoms between placebo and vaccine groups were noted [29], [31].
At the end of the three growth trials, no significant differences were found in final biomass, final mean weight, percent weight gain, feed conversion ratio, and survival.
For both trials, no significant differences were detected between the treatments for BA, before and remaining after the first and second thinning (see Little 2007 for results for first thinning), and for Vol, before and after the second thinning (Table 3).
Unless otherwise indicated, all values (n = 9) were the means of 3 independent trials (no significant differences were observed between individual replicates) ± standard deviation (SD).
During expected trials, no significant differences were found between RP1 and RP2 both for frequency and for duration of reaches (frequency: T+ = 10, N = 6, P = 1.0, two-tailed; duration: T+ = 7, N = 8, P = 0.148, two-tailed; Fig. 4).
However, during expected trials, no significant differences were found between RP1 and RP2 both for frequency and for duration of reaches (frequency: T+ = 9, N = 6, P = 0.813, two-tailed; duration: T+ = 9, N = 8, P = 0.250, two-tailed, Fig. 6).
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The trial also stated no significant differences between groups in the mean number of days for which patients reported being unable to perform daily activities due to illness.
At the end of the trial, no significant differences were observed for either the main effects or their interaction in any of the growth parameters evaluated.
Of the 40 patients who had completed the trial, no significant differences in baseline headache frequency, duration and severity was found between the four treatment arms.
However, as in the previous trial, no significant differences in the severity of the clinical signs, bacterial isolation from blood and organs (data not shown), nor in mortality (LogRank test, p = 0.388) (Figure 8B), were observed between the WT and mutant groups.
In conclusion, in this trial no significant differences were demonstrated in efficacy between the two groups.
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