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Here, randomised trials may not be quite so helpful.Go back to the bednets once more.
The findings indicate that testing combination treatments at only one time point, whether in lab experiments or clinical trials, may not tell the whole story.
Mr Musharraf's trials may not have much impact on the coming elections, but could serve as somehow useful to the army in the post-election period.
Four senior Khmer Rouge officials who were in a position to give those orders are also in custody, but court officials say their trials may not start until next year.
Recently registered diabetes trials may not sufficiently address important diabetes care issues or involve affected populations.
So the important question about Genzyme's gene therapy trials may not be whether they will produce a valuable medical treatment but whether they risk liability.
Antierens agrees that such trials may not detect small effects of a drug, but says the goal is to determine whether an intervention is worthless or clearly works.
If these two methods would identify the same patients as being at risk of future stroke, clinical trials may not need to be restricted to centres with PET facilities.
It should be noted, however, that the baseline plasma zinc concentrations reported in trials may not fully capture the state of zinc deficiency in the children.
In particular, the NIH Division of AIDS (DAIDS) table for grading the severity of adult and pediatric adverse events (http://www3.niaid.nih.gov/research/resources/DMIDClinRsrch/toxtables.htm) used in many clinical trials may not reflect locally established country specific reference ranges.
HSTCL incidence is very low, and clinical trials may not provide a follow-up period that is sufficiently long enough to detect overt lymphoma development in the studied cohorts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com