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These results in a clinical-practice setting demonstrate the long-term efficacy of alfuzosin 10 mg and indicate that the efficacy observed in short-term clinical trials is maintained for at least 2 years.
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All trials were maintained using standard cultural practices appropriate for the region.
Fish from the same fresh and brackish marshes sampled in the earlier trials were maintained in freshwater conditions and allowed to reproduce.
It is therefore important the research community consider supporting the creation of a new infected erythrocyte inoculum or in vitro culture expansion of the existing inoculum, so that, if applicable, safety data may begin to be amassed and provision for the assessment of future BSV candidates by blood-stage CHMI trials be maintained.
An independent data monitoring committee׳s (IDMC׳s) duty is to ensure that the interests of the patients entered in the trial are being well served (i.e., the risk-benefit ratio is appropriate) and that the scientific integrity of the trial is maintained during the interim between trial initiation and trial completion.
To determine whether the efficacy and safety achieved with 2.0 mg intravitreal aflibercept injections (IAIs) for diabetic macular edema (DME) during the phase III VISTA DME trial were maintained with individualized, as-needed treatment.
Dissolved oxygen during the growth trial was maintained at approximately 8.5 mg/L.
Because there is no evidence on the long-term outcomes of anti-VEGF therapy on either VA or CS, it was assumed that transition rates estimated from the 54-week trial were maintained to 5 years.
Elderly patients treated with IFN- α in a randomized phase III study vs sunitinib in the first-line setting (Motzer et al, 2007, 2009) also derived similar benefit as younger patients randomized to IFN- α; however, the survival benefits of sunitinib over IFN- α in this trial were maintained in both age groups.
The CENTRAL database is a general list of clinical trials that is maintained by the collaborative efforts of multiple Cochrane specialty groups.
Furthermore, a one day workshop will be run midway throught the trial to ensure that good practice is maintained.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com