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The trials included almost a quarter-million participants, including healthy people and those with various diseases.
Trials included hanging salamis up the chimney; the salamis developed awful black moulds.
All trials included bipolar patients exclusively.
Several trials included a third active treatment arm.
Only 5 trials included were comparative studies (retrospective cohort studies) while 31 trials included were case series reports.
The analysis of patients' characteristics reveals that most of the trials included heterogeneous populations.
Two trials included participants with bipolar II disorder (Amsterdam and Shults [2010]; Kane et al. [1982]).
Notable limitations of included trials included poor reporting and limited blinding.
The eight trials included a total of 3,355 participants meeting the eligibility criteria.
Additionally, all trials included in our analysis compared changes in clinical endpoints rather than fitness.
However, none of these trials included patients with lymph node invasion (LNI).
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