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Can smartphone drug trials improve medical care?
Could crowd-sourced clinical trials improve drug development success?
Pragmatic trials improve the knowledge base for clinicians, patients, regulatory and funding bodies as well as manufacturers of medical products.
These studies suggest that the addition of MRI/3D-MRSI data to prostate-specific antigen and biopsy data may improve patient selection and risk stratification for chemoprevention trials, improve tissue sampling for ex vivo molecular marker analysis, and provide shorter-term endpoints in chemoprevention trials.
But when we consider the extent to which we can accelerate clinical trials, improve patient outcomes and make the best care available when it's needed most, it's clear that we have to keep working toward those goals.
"I decided to look for a workout that would help me maintain my running skills and build better muscle tissues which, according to evidence-based clinical trials, improve our body's sensitivity to and utilization of insulin," Khoury said.
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(Ultimately, Iressa was not approved; few patients in Phase III trials improved on the drug, and its use is now restricted to those patients).
Adequate reporting of clinical trials improves transparency, and aids interpretation and replication of studies.
The overall quality scores in homeopathic trials improved somewhat from 1945 to 1995.
However, these clinical trials improved outcomes for circumscribed patient populations (6– 9).
Averaging across trials improves the precision, which is advantageous given the relatively low trial-by-trial resolution (each clock 'minute' position corresponding to an interval of ∼43 ms).
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