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The consistency of data from three of the 4 trials implies that a "network-wide" acceptance criterion could be set.
The screening purpose of phase II trials implies that they are designed to reject a new therapeutic regimen showing low therapeutic activity.
9 While we cannot calculate the chance of a favourable outcome given the company's funding, the observation that such trials report larger SMDs compared with independent trials implies that a favourable outcome is more likely in industry-funded trials.
The fact that CDK9 inhibition was found to be nontoxic in clinical trials implies that normal cells have possibly developed coping mechanisms that might not be present in transformed cells.
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In contrast, J-PAL's trials imply that there is a role for outsiders to improve the decision-making of the poor by, say, improving information or incentives.Over the past ten years, randomised trials have changed hugely.
However, there clearly are certain jobs where we have to pay people to do a task, and then pay them again to do it properly.Bob Walder LondonScientific newsSIR – Your article on the suppression of "unfavourable information" about drug trials implied that academic journals have some sort of duty to publish negative results for the public good ("Absence of evidence", November 29th).
And current pre-clinical and clinical trials implied that combination therapies using anthracyclines with immunotherapy have further enhanced the clinical benefit.
The typical low accuracy rates on the conflict trials imply that the ratings for correctly solved conflict problems will be based on a small number of observations which might compromise the reliability of the data.
Data from clinical trials imply that there might indeed be positive effects of insulin therapy for the microvasculature [ 10] while there seem to be limited effects on macrovascular events in the ORIGIN and UKPDS trials [ 11, 12].
But that kind of popularity is bound to attract another kind of attention: the ire of mobile carriers who can start losing messaging revenue in Saya's target markets if this begins to take off as the trial implies that it might.
The fact that we did not find a statistically significant difference with respect to ventilator-free days in this subgroup of patients from the original trial implies that this is a small group of patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com