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11– 16, 16– 18, 20– 26, 26 It appears that none of the trials has been designed and conducted in accordance with the CONSORT statement.
While none of the aforementioned comparative trials has been designed to assess outcomes under double-blind conditions for longer than five years, longer term, open-label, follow-up data are available.
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A number of trials have been designed based on this strategy, and some have supplemented TLR treatment with chemo- and radio-therapies.
Care trials have been designed to simultaneously offer yet-to-be validated interventions and verify treatment outcomes.
Further clinical trials have been designed to test the safety and efficacy of HypoARC in other tumor types.
Regional and national trials have been designed to address various questions that concern the application of this technique.
As a result, a smaller benefit of surgery, such as reduction of risk of loss of three lines of vision, which many trials have been designed to detect, could not be confirmed.
Recent high profile trials have been designed to assess PFS using a randomized discontinuation design and disease control rate after 8 weeks of treatment.
Four ongoing trials have been designed and sufficiently powered to determine whether statin therapy reduces the risk of death and reinfarction when initiated early in ACS treatment.
Based on recent experimental data, a number of clinical trials have been designed for the intravenous (IV) and/or intrathecal (ITH) administration of BMSCs in MS patients.
Because cytotoxic T lymphocytes (CTL) are able to recognize and lyse malignant cells, many therapeutic trials have been designed to potentiate CTL responses.
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