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There is a dual focus on how to design trials for testing both safety and efficacy.
By so doing, the number of trials for testing various ingredient formulae can be reduced, minimizing the ingredient waste.
We conclude that there is sufficient preclinical data to give serious consideration to Phase I trials for testing the antisense ODNs, first and later the AAV.
For cancer drugs that significantly shrink tumors, response (CR and PR) rate is usually the primary endpoint in cancer phase II trials for testing H0: P ≤ P0 vs H1: P ≥ P1, where P0 and P1 are response rates which does not or does warrant further investigation given the rate of false positive and false negative.
We included thus all trials for testing the classifier (disregarding the trial type, correctness, retrieval confidence, or run).
However, the 10-year results of ongoing clinical trials for testing the clinical benefit of gene signatures will not be fully available until 2020 [ 19].
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Some doctors criticized the organizers of the trial for testing Lucentis rather than another Genentech drug, Avastin, which works in the same way as Lucentis.
A two-stage adaptive procedure is developed in order to determine the sample size and the decision rule for the pivotal trial, for testing average bioequivalence using the two one-sided test (TOST).
The Basement provided the perfect trial for testing the friends-without-benefits relationship Amber and I had forged.
Having a pilot study between feasibility studies and trial was important for testing trial and clinic procedures, gel distribution, etc., but also for piloting the combination of methods and the triangulation procedures.
This study will probably be less a clinical study than a trial run for testing in a possible future outbreak, since many of the participants are already taking antibiotics that would have killed off the infections.
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CEO of Professional Science Editing for Scientists @ prosciediting.com