Only 5/38 (13.2%) of the trials provided justification for the predicted delta.
An event-related analysis was used for all trials (no modelling of epoch/block effects); for justification and details, see Mechelli et al. (2003).
Rather, CE embodies a democratic ideal in which legitimacy emerges from deliberative processes through which disagreement is acknowledged and addressed, lines of accountability are established between the stakeholder community and researchers, and stakeholders are empowered to ask directly for justification regarding the trial's conduct and management.
Finally, results from this study are to provide information for justification and design of clinical trials.
Given the high mortality associated with AKI, the lack of specific RRT interventions shown to reduce mortality, and current practice variation, the results of our pilot trial provide justification for a larger trial of hemofiltration vs. hemodialysis that will be adequately powered to evaluate meaningful clinical outcomes.
For each trial with a delay of ≥300 ms, we considered time points ≥160 ms after maze onset (see above for justification of timing).
This pilot trial provides feasibility data for undertaking a larger, powered randomized controlled trial, and provides justification for the importance of environment in relaxation interventions.
In summary, the trends in this pilot study provide (i) evidence of the efficacy of advanced PCDs with truncal treatment, (ii) data to power future evidence-based efficacy trials, and (iii) justification for longitudinal studies to better deploy existing and new treatments to better manage and possibly prevent BCRL.
But those are simply there for justification.
HDL-size and HDL-p, assessed using the LipoScience ALP method, were compared to classical biochemistry measures of HDL-c and ApoA1 in 10,886 participants without CVD in the JUPITER trial (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) [56].
