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Researchers have conducted pharmacogenetic trials for improving the efficacy of four drugs to treat AUD: naltrexone and acamprosate as well as two off-label medications, ondansetron and topiramate.
The Cochrane review of pharmacological and nutritional treatment for McArdle disease includes the evidence from randomized controlled trials for improving exercise performance and quality of life in McArdle disease (Quinlivan et al., 2010).
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They had methodological reasons for this, as they undertook a medication trial for improving cognitive symptoms.
Kilkenny et al. (2010) advocated adopting the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines for reporting animal experimental data in health sciences, noting the success of the Consolidated Standards of Reporting Trials (CONSORT) guidelines for improving the quality and transparency of data reporting from randomized clinical trials.
Trial registration may be a valuable mechanism for promoting transparency in clinical trials, but methods for improving compliance with the provision of registration data should be established.
Such clinical trials are critical for improving outcomes for pancreatic cancer patients.
An increasing number of journals demand that submissions adhere to the Consolidated Standards for Reporting Trials (CONSORT) guidelines for improving report quality [ 1].
The goal, says Barsan, is to use an existing neurological trials network as a laboratory to examine this strategy for improving trials.
See also Table 5. Perinatal mortality - trials had mixed results for improving rates of perinatal deaths, contributing to substantial heterogeneity for this outcome.
Such conditions may be associated with an increased bleeding risk but occur in a relatively small proportion of patients presenting with severe sepsis; pooling data across clinical trials provides an opportunity for improving the characterization of outcomes.
Califf is "a soft-spoken Southerner with a passion for improving clinical trials," and extensive knowledge of industry, Nature's Heidi Ledford reported earlier this year.
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