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Hype Equals Ratings Sunday's much-anticipated 200-meter showdown between Maurice Greene and Michael Johnson at the United States Olympic track and field trials fizzled when both runners pulled hamstrings.
But most trials fizzled.
While the two HGS trials were under way, lupus trials fizzled at several other companies.
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At the end of that same week, after the trial fizzled out, Bryan suffered a massive stroke and died.
In another instance AstraZeneca staged trials that fizzled but used them for a new ad claim anyway.
But Mr. Suozzi's trial balloon quickly fizzled.
The drug examined in this study, Iressa, was the first EGFR inhibitor to come on the market in 2003, but its initial hype fizzled after larger trials showed that it did not lengthen survival for patients in the United States.
It worked well in animals but fizzled in human trials in the mid-1980s.
According to Hersh's account, eleven other men were charged with murder, maiming or assault with the intent to commit murder, but their cases either fizzled out before trial or they were acquitted.
Regulators shot down treatments for multiple sclerosis and premature labor, and medicines for stroke and diabetes fizzled in large-scale trials.
Former highflier AtheroGenics filed for bankruptcy in October; its heart drug fizzled in a big trial in 2007.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com