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Standard analyses of continuous data from such trials fail to recognize the random nature of the stratum sizes.
Despite the efforts that are put into trial design, many trials fail to show an effect of the intervention.
In the third phase ("Trough of Disillusionment"), interest wanes as trials fail to deliver results and press coverage turns negative.
Randomized controlled trials fail to find benefits as well, with the exception of specific cases — for example, preventing the recurrence of some kinds of kidney stones.
As a result, about 40percentt of all oncology clinical trials fail to meet their minimum patient enrollment, which has a major impact on cancer research.
Yet a substantial number of trials fail to reach recruitment goals a situation that has important scientific, financial, ethical, and policy implications.
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But trials failed to show a benefit over placebo.
She thought the trials failed to understand the man and his deeds.
Our trials failed to show that homeopathy is more than a placebo.
Surprisingly, large clinical trials failed to demonstrate a benefit of anti-TNFα strategies23,24.
Juries in the other two trials failed to reach a verdict.
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