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Several ongoing clinical trials evaluate their use as diagnostic [1] or as therapy response assessment [2, 3] tools.
Several issues impact the search for disease-modifying therapies, including appropriate selection of potential therapeutics, developing the appropriate trial designs, ensuring early-stage trials evaluate dose response and biological activity in addition to safety and tolerability, and choosing relevant and easily interpretable outcome measures.
These cluster randomised controlled trials evaluate a comprehensive range of healthcare utilisation outcomes and mortality.
Ongoing clinical trials evaluate the triple chemotherapeutic approach Folfoxiri combined with single or dual targeted agents [ 18– 20].
In contrast exploratory trials evaluate complex interventions in controlled experimental conditions and in a prototype or idealised form [ 49].
The aforementioned observations are certainly relevant and timely as ongoing clinical trials evaluate the benefits of neoadjuvant angiogenesis inhibitors in several cancer types.
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Seven trials evaluated hyperoncotic 20%to25%5% albumin, and four trials evaluated hyperoncotic 10% HES.
This time she elected to participate in one of the trials evaluating the new first-trimester ultrasound test.
The findings, published in the journal Cell, have implications for the design of clinical trials evaluating the benefits of nutrition to patients with sepsis, say the scientists.
The group added that the clinical trials evaluating mammography had imperfections, leading it to regard the evidence as "fair" rather than "good".
The remaining four trials evaluated different models of TC intervention.
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