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These trials documented a significant reduction in adenoma formation in patients at high risk for colorectal cancer, with reductions in advanced disease occurrence from 28 66% over 3 years.
The trials documented in the report generally aimed to streamline access to existing government programs and improve efficiency.
The two pivotal trials documented a strong influence of the applied lamp sources on PDT efficacy.
Most trials documented relevant medical history, such as previous NSAID use or intolerance, or use of prophylactic low-dose aspirin.
The first of these trials documented outcomes in 676 patients with previously treated advanced melanoma (Hodi et al, 2010).
Notably, four of six trials documented lower respiratory tract infections non-systematically as adverse events, 48505253 53 rather than as primary or secondary outcomes.
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As a consequence, clinical phase I trials document a wide range of side effects.
Multiple, prospective trials have been performed comparing open and endovascular TAA repair with three company sponsored trials documenting clinical equipoise.
Widespread application of transjugular intrahepatic portasystemic shunt (TIPS) continues despite the lack of trials documenting efficacy superior to surgical shunting.
Despite extensive clinical trials documenting efficacious clinical response to therapy, there is a paucity of data investigating the molecular mechanisms by which etanercept modulates the improvement of psoriasis.
Its use in trauma patients has been described, but currently there are no published prospective randomized control trials documenting its benefits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com