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In these previous trials, direct visual coregistration between PET/CT data and pathologic slices was performed.
To overcome the drawbacks of single trials, direct and indirect comparison meta-analyses have been designed and conducted to thoroughly compare sirolimus- vs paclitaxel eluting-stents.
We therefore designed the DIabetic REtinopathy Candesartan Trials (DIRECT) Programme to assess whether candesartan could reduce the incidence and progression of retinopathy in type 1 diabetes.
There were a total of 39,004 participants in the placebo controlled trials Direct placebo comparison results suggest all treatments are more effective than placebo with statistical significance in regards to 2 h-pain-free and 2 h-pain-relief (OR > 1, 95% CI excludes 1).
1 A standard pairwise meta-analysis, however, can only compare two treatments (or classes) that have been directly compared in head to head trials (direct evidence).
Due to a great variability of evaluation tools and analytical methodology across trials, direct comparison and pooling of the data was restricted.
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In this review, past and present immunotherapy trials directed at GD2 will be summarized, highlighting the lessons learned and the future directions.
Now he's tackling a Puritan: he stars as John Proctor in a Broadway revival of "The Crucible," Arthur Miller's McCarthy-minded drama about the Salem witch trials, directed by the Belgian experimentalist Ivo van Hove.
Davies, though, argued that the trials directed against beta-amyloid are "targeting the scars of the disease, the lesions the disease produces, without targeting the process that produces the lesions".
It begins with an offbeat production of Robert Ward's stiff but tuneful opera (based on the Arthur Miller play about the Salem witch trials), directed by Robert Alföldi, the enfant terrible of Hungarian theatre.
In addition, there have not been any trials directed specifically at enteroendocrine cell function in IBS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com