Both WH6725 and MH725 had the degree of chalkiness scored as 1 with slight variance in different field trials (Degree of chalkiness or DC: WH6725, 5.8 ± 5.4%; MH725, 4.7 ± 4.0%) (Table 4).
We extracted from the article specific characteristics of NI trials: degree of blinding, the method to determine the NI margin, the type of analysis, the use of a placebo arm to confirm assay sensitivity, and whether the authors discussed the constancy assumption.
Though the mean blood glucose concentration is similar among trials, the degree of glucose variability may be quite different.
Within available trials, the degree to which interventions are explicitly tailored is marginal and often limited to content.
However, within the large number of available trials, the degree to which interventions are explicitly tailored is marginal.
In a pooled, retrospective analysis of patients with mRCC treated with sunitinib, interferon-alfa, axitinib, sorafenib, temsirolimus, or temsirolimus plus interferon-alfa in phase II or III clinical trials, the degree of tumour shrinkage correlated with OS, and maximal tumour shrinkage (−100% to −60%) was an independent predictor of OS (Grünwald et al, 2013).
Dickerson and colleagues found that, in mildly impaired aged individuals who did not meet strict MCI criteria as implemented in clinical trials, the degree of cognitive impairment in daily life and performance on neuropsychological testing impacted the likelihood of an AD diagnosis within 5 years [ 32].
Given the pragmatic focus of the trial, the degree of adherence to treatment protocols is of considerable interest.
In the current trial, the degree of sensations, pain and fatigue measured separately on the VAS scale did not decrease, and yet the QOL sub-scale of symptoms, consisting of a combination of six different symptoms, improved significantly, indicating a reduction in the adverse effect of symptoms on women's QOL.
In accordance with guidance for controlled trials, [11] the degree of headache severity was rated on a 4-point scale to indicate severe (3), moderate (2) or mild (1), or headache-free (0).
Through correlation and linear regression analyses of the number of approvals and trials, and weighted degree values, with the cancer lethality values, we assessed whether the death statistics impact the formation of associations between the cancers and drugs.
