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Potentially heterogeneous definitions of myocardial infarction used across the trials could represent another limitation.
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For instance, based on our results, exploring the activity of the small molecule CC-115, a double inhibitor of mTOR and DNA-PK, currently tested in a phase I clinical trial, could represent a promising strategy for the treatment of selected EOC patients expressing high levels of stathmin and p53 proteins.
Reports that some participants wore wristbands inappropriately, and/or delayed completion of trial paperwork could represent confounding variables and have implications for the trial results, and the design of clinical trials within the field of cancer.
AUD and VIS trials could be considered as representing a conflict scenario, in that there is no coherent signal in the other sensory modality.
* The trials could be held in secret.
Additional trials could be helpful to clarify this point.
If confirmed in randomized trials, vitamin D supplementation could represent a simple and inexpensive method to prolonging the time to initiation of antiretroviral therapy in HIV-infected patients, particularly in resource-limited settings.
In different trials, the same offer amount could represent a larger percentage of the total stake and could, therefore, seem fair, or it could represent a smaller percentage of the total amount and could, therefore, seem unfair.
In order for our pharmacy adherence measure to better reflect adherence as indicated by refills the patient requested, we excluded new medications with only one fill from the calculation because first prescriptions in the VA health system are filled automatically without effort required by the patient, and because single fill medications could represent a trial of new medication.
Results from these trials suggest that anti-NGF therapy could represent an important new class of therapy for pain management in chronic pain conditions.
It has applied the OMERACT filter to individual tools that could represent endpoints in trials and has critically reviewed the published literature to explore the extent to which outcomes have been validated.
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