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An inquiry by the Department of Health, the results of which were published in 2000, concluded that although the trials complied with rules in force at the time, sufficient safeguards to fully protect parents and children were not in place.
Two trials complied with the definition of using electronic feedback [ 14, 15].
Overall, a median, per drug, of 71% (IQR 0 100%) of applicable trials complied with FDAAA (see table 2).
All trials complied with the Declaration of Helsinki and were approved by the locally appointed ethics committee of each participating centre.
Two companies in our sample acquired or licensed drugs initially developed by smaller companies, and another used a partner company for some trials, raising questions about whose responsibility it was to ensure trials complied with FDAAA.
All four randomized clinical trials complied with at least one of the criteria in the guidelines for assessment of the quality of reports of randomized clinical trials of Jadad and colleagues [ 6].
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The prophylactic trials comply well with using the recommended primary efficacy measure.
The linked trials comply with the Declaration of Helsinki and Good Clinical Practice.
We also recommended that future trials comply with international standards in the evaluation of treatment effects.
3 5 Table 1 shows previous studies' findings on inadequate reporting of specific aspects of trial interventions within a range of treatment areas; for example, an evaluation of trials complying with item 4 of the CONSORT statement.
The trial complied with the institutional guidelines of the animal welfare and husbandry for monkeys.
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CEO of Professional Science Editing for Scientists @ prosciediting.com