Sentence examples for trials combination from inspiring English sources

Although both TRAIL and agonistic antibodies against DR4 and DR5 are in clinical trials, combination with nutraceuticals is likely to boost their anticancer potential.

After 50 years of almost entirely empirical clinical trials, combination chemotherapy moved the prognosis of standard childhood leukemia from invariably fatal to an 85% cure rate [ 4].

The methodologies of five meta-analyses were reviewed in terms of the included trials, combination of data, choice of outcome, and analysis methods.

There were only a few trials evaluating new drugs, such as erlotinib, lapatinib, dolastatin, exatecan, rebeccamycin (one trial each, monotherapy), and raltitrexed (two trials, combination with gemcitabine and cisplatin/epirubicin, respectively).

In some studies, the vitamins have proved to be worse than placebos, while in other trials, combinations of vitamins have actually reduced the benefits of proven treatments.

In many of these trials combinations of more antioxidants were assessed.

In the ONTARGET trial combination therapy reduced proteinuria to a greater extent than monotherapy, however, overall renal outcomes were worse with combination therapy [38].

In this multicenter phase III randomized trial, combination of paclitaxel plus epidoxorubicin gave a higher response rate than single agent paclitaxel.

In another randomized trial, combination therapy with methotrexate, sulfasalazine, and hydroxychloroquine resulted in better remission rates than single treatment in early RA (category A) [ 40].

In another recent phase III trial, combination therapy with motesanib, another antiangiogenic TKI, plus paclitaxel/carboplatin also failed to prolong OS [ 15].

In both trial combinations, target-related response biases produce stimulus-response interference because a non-target response is required.