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Through case examples, this paper will discuss how advanced imaging is currently being investigated in oncology clinical trials, categorized by the potential clinical indication for the imaging tool and offer suggestions on how development should proceed to further evaluate imaging in the given indication.
Although all of the scales we used have established reliability and validity estimates, we found that the number of trials categorized as high quality or low quality depended specifically on the scale that was applied.
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Conversely, an additional trial, categorized as longitudinal in the 2004 review, but reassessed by us as randomized control, was added to the test/feedback category [ 24].
The core clinical trial categorized subjects switched from olanzapine or quetiapine into the sedating antipsychotic group and patients switched from risperidone, aripiprazole, or ziprasidone into the non-sedating antipsychotic group a priori to the study [ 25].
TB suspects who had three negative smears and suggestive X-ray findings or failure to respond to an antibiotic trials were categorized as smear negative pulmonary TB.
The data obtained in the remaining trials were categorized into three main different subsets according to their relevance to distinct behavioral constructs [54], [55], [56], [57], [58].
Most of the trials were categorized in this range.
The quality of all the included trials was categorized to low/unclear/high risk of bias.
The quality of all the included trials was categorized as "low risk", "high risk" or "unclear risk".
For instance, it would be helpful to see whether the results hold if trials were categorized to less-than-average and more-than-average reward sizes.
These clinical trials are categorized by their primary intention, ie, according to whether they are studies of rhythm control, rate control, mortality/morbidity, or comparative efficacy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com