Sentence examples for trials big from inspiring English sources

Settlements silence: By avoiding the publicity of trials, Big Pharma buries facts that could harm their reputation and cut profits.

This is different from sequential adjuvant trials (BIG 1-98 sequentiarmsrms and TEAM), which include all recurrences after randomization in their efficacy analysis, including events during the early peak at 2 to 3 years [ 2, 4].

Even now, with the first defendant finally on trial, big questions about the process remain unresolved.

That being said, WhatsApp in the past has trialled big updates to its apps in a similar fashion.

Their skirmishes put on trial Big Pharma's role in the development and distribution of AIDS drugs, and the FDA's red tape and glacial pace.

Molecular scores were validated in an independent set of tumor tissues from 342 participants of trial BIG 1-98.

Unlike the ATAC trial, BIG 1-98 required patients' tumors to be HR+, defined as positive for ER, PgR, or both [ 11].

The current study is a retrospective study on primary tumor samples from a larger population of patients participating in the clinical trial BIG 02-98.

Independent FFPE blocks and corresponding clinical data of 437 Swiss participants of the trial BIG 1-98 were provided by the International Breast Cancer Study Group.

Letrozole, by significant inhibition of production of oestrogen can cause bone loss and increased incidence of fractures, its main adverse effect in the elderly as shown in the large adjuvant letrozole trial BIG 1 98 (Crivellari et al, 2008).

Interestingly, the letrozole trial (BIG 1-98 trialsoalso evaluated the sequential approach (2 3 years of tamoxifen followed by letrozole for a total of five years or three years letrozole upfront followed by tamoxifen for a total of five years), but data from these arms are not yet available.