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But researchers may struggle to take the drug into large human trials because it is off-patent and so difficult for a funder to recoup costs from.
'Look, we've done it on the local level in Baghdad, and it works".' Some of the human rights advocates also contend that the administration wants to maintain control of the trials because it is concerned that the trials might turn up evidence of American complicity in some of Hussein's atrocities.
Melatonin has been considered to hold therapeutic properties on headache profiles due to its normalizing effects on circadian rhythms and sleep and was further pursued in controlled trials because it is non-toxic, low cost and easily available over the counter in most countries (see Table 2) [119] 119].
Indirect evidence may be considered of lower quality than evidence from head to head trials because it is prone to similarity/transitivity problems.
The FSS was selected to measure fatigue in the simeprevir trials because it is a brief, patient-reported outcome (PRO) measure of the impact of disabling fatigue on daily functioning in patients with chronic illness [ 13].
This is entirely reasonable in the context of smoking cessation trials, because it is plausible that there is an association between participants' smoking status and the probability that this status is observed.
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I think what's going on here is the kind of stuff you and I saw in law school, right: all these academic debates, all these liberals – 'oh, we got to show the world we're better than that!' And I think they prefer the civilian trials because it's more likely the terrorists will be able to game the system.
In previous years we've been critical of the trials because it's been quite obvious who was going to make the team.
"Calorie restriction has failed miserably in human trials" because it's so hard to stick to, says gerontologist Rafael de Cabo of the U.S. National Institute on Aging in Baltimore, Maryland, who leads one of the monkey studies of calorie restriction.
Matt Bowden scoured the scientific literature, found an antidepressant that failed clinical trials because it was attractive to stimulant users, and decided to use and it and sell it as a safer alternative to methamphetamine, which was then ripping through the local rave scene.
For one, attention may have been guided to the second exemplar in the category-match trials because it was visually similar (although not identical) to the memory item.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com